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Symbol
Name
ID

Abcc8
ATP-binding cassette, sub-family C member 8
MGI:1352629

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Type I diabetes mellitus	Type II diabetes mellitus	Hyperinsulinemic hypoglycemia	Pancreatic islet-cell hyperplasia
Disease(s) Associated with ABCC8	Diabetes mellitus	Type I diabetes mellitus	Type II diabetes mellitus	Hyperinsulinemic hypoglycemia	Pancreatic islet-cell hyperplasia
familial hyperinsulinemic hypoglycemia 1
leucine-sensitive hypoglycemia of infancy
permanent neonatal diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes		abnormal pancreatic beta cell morphology	abnormal insulin secretion	decreased insulin secretion	increased insulin secretion
Availability	Mouse Genotype	abnormal pancreatic beta cell morphology	abnormal insulin secretion	decreased insulin secretion	increased insulin secretion
	Abcc8^tm1.1Fmas/Abcc8^tm1.1Fmas
	Abcc8^tm1.1Mgn/Abcc8^tm1.1Mgn
	Abcc8^tm1Jbry/Abcc8^tm1Jbry
	Abcc8^tm1.1Fmas/Abcc8⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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